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BSID Annual Meeting, Surgeons' Hall, Edinburgh, 12-14 April 2010
Delegates with electronic access to the British Journal of Dermatology can download all abstracts from the meeting here.
Monday 12 April 2010
| 12:45-13:30 |
TRAINEE LECTURE:
More late night thoughts on clinical science and practice
Professor Jonathan Rees, University of Edinburgh |
| 14:00 |
Welcome: Edel O'Toole, Chair BSID |
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BSID SKIN CLUB SYMPOSIUM:
Inflammatory Skin Disease
Chairperson: Richard Weller
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| 14:00-14:35 |
Mechanisms linking innate and adaptive immunity
Prof. Jürgen Schwarze, University of Edinburgh |
| 14:35-15:10 |
Genetics of atopic dermatitis: a tail of mice and men
Prof. Padraic Fallon, Trinity College, Dublin |
| 15:10-15:45 |
The role of pharmacogenetics in inflammatory skin disease
Dr Richard Warren, University of Manchester |
| 15:45-16:15 |
Coffee/Tea |
| 16:15-16:50 |
Anti-TNF as a tool to unravel human immunity in patients with rheumatoid arthritis
Prof. Michael Ehrenstein, University College London |
| 16:50-17:30 |
BSID Medal Lecture
The long haul and the butterfly effect - in pursuit of answers to interesting questions
Prof. Peter Friedmann, University of Southampton |
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| 17:30-19:30 |
Poster session |
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| 19:45 |
Dinner |
Tuesday 13 April 2010
SCIENTIFIC SESSION A Chairperson: Rebecca Porter
| 08:30 |
01 |
Clock genes modulate the human hair cycle: Period1 knock-down in human
hair follicle organ culture prolongs anagen. Y Al-Nuaimi, JE Klatte, BI Tóth, REB Watson, T Biró and R Paus.
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| 08:43 |
02 |
iASPP a novel and essential key regulator of skin homeostasis. A Chikh, R Matin, CA Harwood and D Bergamaschi.
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| 08:56 |
03 |
Varicella-zoster replication and its association with keratin 15 expression and
Wnt signalling. M Singh, J Breuer, R Heseltine, R Cerio, J Millar, MP Philpott and EA O'Toole.
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| 09:09 |
04 |
Increased type VII collagen in adipose derived stem cell-keratinocyte co-culture compared with dermal fibroblast co-culture is dependent on MMP3. C Pourreyron, C Cole, JA McGrath, IM Leigh and AP South.
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| 09:22 |
05 |
The connexin mimetic peptide Gap27 increases cell migration in diabetic conditions in vitro and alters gene expression of dermal fibroblasts. CS Wright and PEM Martin.
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| 09:35 |
06 |
Prostaglandin F2 stimulates human hair follicles via receptors located within
the follicle itself. KG Khidhir, NP Farjo, DF Woodward, SM Picksley and VA Randall.
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| 09:48 |
07 |
Keratinocyte-derived factors stimulate fibroblast hyaluronan synthesis: a
possible role in suppression of scar tissue formation. M Edward and JA Quinn.
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| 10:01 |
08 |
Activation of peroxisome proliferator activator receptor beta/delta in the skin
induces IL1 and STAT3 signalling. M Romanowska, L Reilly, C Palmer and J Foerster. |
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| 10:14-10:45 |
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Coffee/Tea |
SCIENTIFIC SESSION B Chairperson: John Mee
| 10:45 |
09 |
Demonstration of novel innate immune cells in psoriasis skin. RKH Mak, C Hundhausen, E Botti, K Grys and FO Nestle.
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| 10:58 |
10 |
Priming of adaptive immune responses by different subsets of skin dendritic
cells. ME Polak, L Newell, C Pickard, E Healy and M Ardern-Jones.
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| 11:11 |
11 |
Investigating the role of the transcription factor T-bet in the immunopathogenesis of psoriasis. P Di Meglio, Y Umezawa, L Napolitano, E Botti, S Karagiannis and FO Nestle.
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| 11:24 |
12 |
The role of invariant natural killer T cells in psoriasis. AM Tobin, A Hogan, L Lynch, S Rogers, P Collins, D O'Shea and B Kirby.
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| 11:37 |
13 |
A defect of varicella-zoster specific CD4+ T cell infiltration after cutaneous
antigen challenge in ageing. E Agius, M Vukmanovic-Stejic, KE Lacy, T Sobande, J Breuer, GS Ogg, MH Rustin and AN Akbar.
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11:50 |
14 |
Association of decreased CCR5 expression with impaired migration of Langerhans cells (LCs) in early-onset psoriasis. FL Shaw, R Begum, RJ Dearman, I Kimber and CEM Griffiths. |
| 12:03 |
15 |
Development of a novel assay for autoimmune blistering disease. J-BO Barbaroux, JB Mee, HL Kwong and RW Groves. |
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| 12:20-13:00 |
Keynote Guest Lecture
(sponsored by the British Association of Dermatologists)
Desmosomes pull it together: coordinating adhesion and signaling in epidermal differentiation.
Prof. Kathleen Green, Northwestern University, Chicago
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| 13:00-14:00 |
Lunch and posters |
SCIENTIFIC SESSION C Chairperson: Rachel Watson
| 14:00 |
16 |
UVB induces melanosome transfer via filopodia in human skin cells. SK Singh, C Nizard, R Kurfurst, S Schnebert, E Perrier and DJ Tobin.
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| 14:13 |
17 |
Azathioprine withdrawal results in reduction in UVA photosensitivity but persistence of potentially mutagenic DNA thiopurines. NR Attard, G Hofbauer, G Straub, A Serra, CA Harwood, J McGregor and P Karran.
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| 14:26 |
18 |
Melanosomes in pigment cells contain functional MC1R. CL Jackson, SK Singh, SJ Robinson, P Kumar, AM Page, PS Friedmann, DJ Tobin and E Healy.
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| 14:39 |
19 |
p63 is implicated in apoptotic dysregulation in melanoma. RN Matin, A Chikh, G Warnes, CM Proby, IM Leigh, CA Harwood and D Bergamaschi.
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| 14:52 |
20 |
Photoactivation of DNA thiobases: a potential novel phototherapy to kill hyper-proliferative and malignant skin cells. O Reelfs, P Karran, Y-Z Xu and AR Young. |
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| 15:05-15:45 |
British Photodermatology Group Guest Lecture
The measurement of UVR-induced DNA damage in the skin and urine
Prof. Dan Segerbäck, Karolinska Institute, Stockholm
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| 15:45-16:15 |
Tea/coffee |
| 16:15-17:15 |
Annual General Meeting (Last year's minutes) |
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| 19:30 |
Annual Dinner |
Wednesday 14 April 2010
SCIENTIFIC SESSION D Chairperson: Penny Lovat
| 08:30 |
21 |
Lhx2 transcription factor controls the activity of epithelial stem cells in the skin during tumourigenesis and wound healing. AN Mardaryev, AA Sharov, TY Sharova, MY Fessing and VA Botchkarev.
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| 08:43 |
22 |
The role of the receptor tyrosine kinase Axl in intercellular adhesion and signalling in cancer. MA Cichon, IC Mackenzie and EA O'Toole.
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| 08:56 |
23 |
Dysregulated tropomyosin receptor kinase (Trk) signalling in CYLDtrunc/trunc tumours. N Rajan, CJ Lord, O Clewes, J Burn, M Sieber-Blum and A Ashworth.
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| 09:09 |
24 |
Sonic Hedgehog is not enough to create basal cell carcinoma in vitro. C Searby, CM Heard and RM Porter.
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| 09:22 |
25 |
Identification of polo-like kinase 1 as a potential therapeutic target in squamous cell carcinoma. SA Watt, C Pourreyron, J Foerster, C Hogan, K Purdie, L Bruckner-Tuderman, C Proby, JA McGrath, IM Leigh and AP South.
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| 09:35 |
26 |
PTPRD microdeletions are associated with metastatic cutaneous squamous
cell carcinoma. SR Lambert, K Purdie, A Gulati, IM Leigh, DP Kelsell, CA Harwood and C Proby. |
| 09:48 |
27 |
The role of Vgamma9 Vdelta2 gamma delta T cells in malignant melanoma. U Laggner, M Harries, A Hayday, F Nestle and K Lacy.
|
| 10:01 |
28 |
Oncogenic B-RAF signalling confers resistance of metastatic melanoma to autophagy. JL Armstrong, M Corazzari, M Piacentini and PE Lovat. |
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| 10:14-11:00 |
Posters and Coffee/Tea |
SCIENTIFIC SESSION E Chairperson: Simon Meggitt
| 11:00 |
29 |
MicroRNA-31 regulates a complex program of gene expression during hair cycle and associated tissue remodeling. MI Ahmed, AN Mardaryev, N Vlahov, AA Sharov and NV Botchkareva.
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| 11:13 |
30 |
Replication of eczema susceptibility loci identified from a genome-wide association study. SJ Brown, GM O'Regan, LE Campbell, HJ Cordell, AD Irvine and WHI McLean.
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| 11:26 |
31 |
Protease-antiprotease imbalance: a potential confounder in the pathogenesis of eczema. SP Tan, R Weller and SB Brown. |
| 11:39 |
32 |
Translational development of ex vivo gene therapy for Netherton syndrome. E Semenova, W Qasim, F Larcher, G Talbot, AJ Thrasher, JI Harper and WL Di. |
| 11:52 |
33 |
Allele-specific siRNA therapy for epidermolysis bullosa simplex. S Atkinson, VE McGilligan, H Liao, TC Moore and WHI McLean. |
| 12:05 |
34 |
Revertant mosaicism in Kindler syndrome resulting from transcriptional correction of the FERMT1 gene. JE Lai-Cheong, T Techanukul, M Parsons, C Moss and JA McGrath. |
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| 12:20-13:00 |
Distinguished Local Guest Lecturer
Regulation of inflammatory responses by clearance of dying cells
Professor Sir John Savill, University of Edinburgh
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| 13:00 |
Prizes and close of meeting |
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| 13:15 |
Lunch |
Poster list:

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