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BSID Annual Meeting, Royal Agricultural College, Cirencester, 30 March - 1 April 2009
Delegates with electronic access to the British Journal of Dermatology can download all abstracts from the meeting here.
Monday 30 March 2009
| 12:45-13:30 |
TRAINEE LECTURE:
How to approach getting your work published
Dr Clive Grattan, recent past editor, Clin Exp Dermatol |
| 14:00-17:00 |
BSID SKIN CLUB SYMPOSIUM:
Drug delivery and the skin
Chairperson: Richard Weller |
| Welcome |
Graham Ogg, Chairman BSID
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| 14:00-14:40 |
Stratum corneum - a keratinocyte's life after death
Prof. Erwin Tschachler, Medical University of Vienna, Austria
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| 14:40-15:20 |
Assessment of topical bioavailability
Prof. Richard Guy, University of Bath
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| 15:20-15:40 |
Coffee/Tea |
| 15:40-16:20 |
Skin drug delivery: the naked truth revealed
Prof. Marc Brown, University of Hertfordshire |
| 16:20-17:00 |
British Association of Dermatologists sponsored talk:
Overcoming delivery issues in developing siRNA therapeutics
Dr Roger Kaspar, CEO, TransDerm Inc., Santa Cruz, CA, USA |
| 17:00-18:00 |
EDUCATIONAL SESSION
My approach to the investigation of inflammatory skin disease
Prof. Richard Camp, University of Leicester |
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| 18:00-19:00 |
UK Professors of Dermatology meeting
Prof. Jonathan Rees, University of Edinburgh |
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| 19:30 |
Dinner |
Tuesday 31 March 2009
SCIENTIFIC SESSION A Chairperson: Rebecca Porter
| 08:30 |
01 |
Activation of PPAR delta in vivo is sufficient to cause psoriasis-like disease and replicates transcriptional dysregulation. M Romanowska, CN Palmer and JP Foerster.
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| 08:45 |
02 |
MicroRNAs in hair-cycle-dependent gene regulation, hair growth control and associated tissue remodeling. A Mardaryev, MI Ahmed and N Botchkareva.
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| 09:00 |
03 |
AKT-dependent protein phosphatase 2A activity is necessary for epidermal barrier function and the correct formation of the cornified layer. RFL O'Shaughnessy, JC Welti and CR Byrne.
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| 09:15 |
04 |
Lysophosphatidic acid-evoked calcium fluxes promote NFAT-mediated keratinocyte migration. R Jans, AM Brown, S Sikkink, K Ross and NJ Reynolds.
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| 09:30 |
05 |
Varicella zoster virus infection in skin shows prominent involvement of adnexal stem cell compartments. M Singh, J Breuer, R Heseltine, J Millar, MP Philpott and EA O'Toole.
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| 09:45 |
06 |
Investigation of the spatio-temporal expression pattern of the antimicrobial peptide, LL-37, in the development and resolution of psoriasis. GK Perera, D Kassen and FO Nestle.
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| 10:00 |
07 |
A role for STAT4 during mitosis of keratinocytes. C Ferreli, C Pickard, S August, Y Buggy, MR Ardern-Jones, PS Friedmann and E Healy.
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| 10:15-10:45 |
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Coffee/Tea |
SCIENTIFIC SESSION B Chairperson: Edel O'Toole
| 10:45 |
08 |
The identification of primary human cutaneous squamous cell carcinoma stem cells. GK Patel, CL Yee and JC Vogel.
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| 11:00 |
09 |
Targeting XIAP to increase endoplasmic reticulum (ER) stress-induced apoptosis of malignant melanoma. EL Hiscutt, DS Hill, S Martin, R Flockhart, JL Armstrong, S Fulda and PE Lovat.
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| 11:15 |
10 |
Mechanisms of increased invasion of cutaneous squamous cell carcinoma cells with loss of type VII collagen. VL Martins, JJ Vyas, M Chen, KJ Purdie, AP South, A Storey, JA McGrath and EA O'Toole.
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| 11:30 |
11 |
DUSP23, SLCO1B3, SNURF, SNRPN and TJAP1 are genes with differential expression in squamous cell carcinoma keratinocytes derived from patients with recessive dystrophic epidermolysis bullosa. CL Cole, J Foerster, C Pourreyron, K Purdie, C Hogan, C Proby, L Bruckner-Tuderman, JA McGrath, IM Leigh and AP South.
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| 11:45 |
12 |
RasHa activation in Fos/PTENnull skin carcinogenesis interdicts a p53/p21-induced keratoacanthoma aetiology and while p53 loss elicits conversion retention of p21 limits malignant progression. FH MacDonald, D Yao, JA Quinn and DA Greenhaigh.
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12:00 |
13 |
Changes in the density of functioning skin lymphatics around human melanoma. V Akhras, AWB Stanton, RH Mellor, JR Levick and PS Mortimer. |
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| 12:15-13:00 |
Keynote Guest Speaker
Parallels between wound repair and cancer
Prof. Sabine Werner, Swiss Federal Institute of Technology, Zürich, Switzerland
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| 13:00-14:00 |
Lunch |
SCIENTIFIC SESSION C Chairperson: Rachel Watson
| 14:00 |
14 |
Ciclosporin treatment induces oxidative DNA damage. NR Attard, CA Harwood, J McGregor and P Karran.
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| 14:15 |
15 |
Real-time imaging of UVB-induced keratinocyte apoptosis to determine duration of apoptosis and effect on tissue turnover. SC Weatherhead, D Jamieson and NJ Reynolds.
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| 14:30 |
16 |
Overexpression of GLI2 in human keratinocytes results in polyploidy and resistance to UVB induced apoptosis. E Pantazi, G Trigianti, G Warnes, E Gemenetzidis, M-T Teh and MP Philpott.
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| 14:45 |
17 |
UV labile NO stores in the skin may have beneficial cardiovascular effects. S Abeyakirthi, M Mowbray and R Weller.
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| 15:00-15:45 |
British Photodermatology Group Guest Lecture
TBA
Prof. Peter Karran, London Research Institute, Cancer Research UK |
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| 15:45-16:00 |
Tea/coffee |
| 16:00-17:00 |
Annual General Meeting (Last year's minutes) |
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| 18:00 |
Posters and drinks |
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| 19:30 |
Annual Dinner |
Wednesday 1 April 2009
SCIENTIFIC SESSION D Chairperson: John Mee
| 08:45 |
18 |
Innate immune function for HLA-Cw6 in psoriasis: reduced expression of HLA-Cw6 facilitates TNF-alpha release due to impaired interaction with inhibitory receptor KIR2DL1. C Hundhausen, R Mak, E Botti, U Laggner, M Marget and FO Nestle.
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| 09:00 |
19 |
Sensitisation with DNCB results in skewed T cell polarisation in atopic dermatitis. EL Newell, ME Polak, C Pickard, E Healy, PS Friedmann and MR Ardern-Jones.
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| 09:15 |
20 |
Trichohyalin - a potential major autoantigen in human alopecia areata. MC Leung, DA Fenton, CW Sutton and DJ Tobin.
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| 09:30 |
21 |
The skin homing Vgamma9 Vdelta2 T cell - a potential role in psoriasis? U Laggner, P di Meglio, C Hundhausen, G Perera, E Botti, R Mak, AC Hayday and FO Nestle.
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| 09:45 |
22 |
Skin derived dendritic cell control of T cell activation. ME Polak, L Newell, E Healy and MR Ardern-Jones.
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| 10:00 |
23 |
Impaired tumour necrosis factor-alpha-induced Langerhans' cell (LC) migration in early-onset psoriasis: no systemic effect on dendritic cells (DC). FL Shaw, R Begum, M Cumberbatch, RJ Dearman, I Kimber and CEM Griffiths. |
| 10:15 |
24 |
TNF-alpha synthesis by macrophages is impaired during secondary cutaneous immune responses in old subjects. E Agius, K Lacy, M Vukmanovic-Stejic, AP Papageorgiou, S Hall, JR Reed, J Curnow, LS Taams, AL Jagger, J Fuentes-Duculan, C Buckley, M Salmon, J Krueger, J Greenwood, N Klein, M Rustin and AN Akbar.
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| 10:30-11:15 |
Posters and Coffee/Tea |
SCIENTIFIC SESSION E Chairperson: Simon Meggitt
| 11:15 |
25 |
CDKAL1, a possible genetic link between Crohn's disease, psoriasis and type 2 diabetes. M Quaranta, F Capon, MA Allen, AD Burden, R Warren, R Smith, H Young, CEM Griffiths, J Worthington, RC Trembath and JNWN Barker.
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| 11:30 |
26 |
Skin fragility in AEC syndrome is associated with reduced expression of the basement membrane-associated protein FRAS1. SE Clements and JA McGrath.
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| 11:45 |
27 |
Reduced expression of basal keratinocyte stem cell markers and altered integrin profiles in Kindler syndrome skin. JE Lai-Cheong, A Tanaka, M Parsons and JA McGrath. |
| 12:00 |
28 |
A role for p63 in establishing tissue-specific chromatin organisation and high-order chromatin remodelling in epidermal keratinocytes during skin development. MY Fessing, AN Mardaryev, M Gdula, AA Sharov, TY Sharova, AA Panteleyev, C Missero and VA Botchkarev. |
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| 12:15-13:00 |
Local Guest Speaker
Promoting immune regulation as a therapeutic strategy for allergic and autoimmune diseases
Prof. David Wraith, University of Bristol
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| 13:00-13:05 |
Prizes and close of meeting |
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| 13:15 |
Lunch |
Poster list:

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