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BSID Annual Meeting, University
of Cambridge, 11-13 April 2005
Monday 11 April 2005
| 10:30-11:30 |
BSID Committee meeting |
| 11:30-12:30 |
Introduction to dermatological research for
clinical trainees
Prof David Kelsell, Institute of Cell and Molecular Sciences,
London, UK. |
| 13:25-13:30 |
Welcome: Eugene Healy |
| 13:30-17:00 |
BSID SKIN CLUB SYMPOSIUM
- Sponsored by Schering Plough
Chairman: David Kelsell
Genetics of skin disease: what is it telling us? |
| 13:30–14:15 |
Genetics and genomics of atopic
dermatitis
Prof. William Cookson, Wellcome Trust Centre for Human Genetics,
Oxford, UK |
| 14:15–15:00 |
Variation and function of MC1R;
from humans to fish via birds and bears
Prof. Ian Jackson, MRC Human Genetics Unit, Edinburgh, UK |
| 15:00–15:30 |
Coffee/Tea |
| 15:30–16:15 |
Genetics of susceptibility
to infectious diseases
Dr Sarra Jamieson, Cambridge Institute for Medical Research,
Cambridge, UK |
| 16:15–17:00 |
Clinical implications of genetics discovery in psoriasis
Prof Jonathan Barker, St John’s Institute of Dermatology,
London, UK
|
| 17:00-18:00 |
UK Professors of Dermatology meeting |
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|
| 18:30-19:15 |
EDUCATIONAL SESSION -
Chairman: Graham Ogg |
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Sub epidermal bullous diseases:
Clinicians and Scientists
Prof. Fenella Wojnarowska, Dept of Dermatology, Churchill
Hospital, Oxford, UK |
| 19:15-20:00 |
Welcome Reception |
| 20:00 |
Dinner |
Tuesday 12 April 2005
SCIENTIFIC SESSION A – Chairman: Edel O'Toole
| 08:45 |
01
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Downregulation of desmoplakin
by RNA interference in HaCaT cells results in
increased cellular proliferation. H Wan and IR Hart. |
| 09:00 |
02
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Laminin-3: novel multiple isoforms
imply a range of tissue-specific functions. KJ Hamill
and WHI McLean. |
| 09:15 |
03
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Elucidation of connexin31 as a
regulator of epidermal differentiation and tissue homeostasis.
T Aasen, W-L Di and DP Kelsell. |
| 09:30 |
04
|
Functional effects of pachyonychia
congenita type I mutations on keratinocyte migration and proliferation.
CJ Fitchett, EI Rugg, N Gilfillan, IM Leigh and EA
O’Toole. |
| 09:45 |
05
|
Tight junction claudin expression
and the effect of exogenous TNFa
exposure. I McGuill, CA O’Neill, R Poddar, CEM
Griffiths and REB Watson. |
| 10:00 |
06
|
Melanocortin 1 receptor
genotype and phaeomelanin/eumelanin ratio in untanned Caucasian
skin. S Robinson, S Dixon, A Collins, C Gough, K Wakamatsu
and E Healy |
| 10:15-10:45 |
|
Coffee/Tea |
SCIENTIFIC SESSION B – Chairman: Marie Cumberbatch
| 10:45 |
07
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Inhibition of calcium-independent
phospholipase A impairs lysophosphatidic acid-induced calcium
entry in keratinocytes. K Ross and NJ Reynolds. |
| 11:00 |
08
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Dithranol induces cytochrome
c release, caspase 3 activation and apoptosis in human keratinocytes.
NJ Reynolds, A McGill, A Frank, N Emmett, L Skitt,
DM Turnbull and MA Birch-Machin. |
| 11:15 |
09
|
Impaired Langerhans cell migration
in psoriasis: an analysis of cutaneous cytokine/receptor expression.
M Cumberbatch, M Sinch, M Bhushan, H Young, RJ Dearman, I
Kimber and CEM Griffiths. |
| 11:30 |
10
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Novel autoantigens in the proteome
of psoriatic epidermis. RG El-Rachidy, JM Hales, PPE
Freestone, CRA Hewitt, JE Osborne and RDR Camp. |
| 11:45 |
11
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VEGF-A induced psoriasiform inflammation
is ameliorated by blockade of VEGF receptor-3. HS Young,
C Halin, L Janes, M Min, B Pytowski, CEM Griffiths and
M Detmar. |
|
12:00
|
12
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IgGs reactive with proteins secreted by Streptococcus
pyogenes are more abundant in serum from patients with
chronic plaque psoriasis than healthy controls. RG El-Rachidy,
JM Hales, PPE Freestone, CRA Hewitt, JE Osborne and RDR
Camp.
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| |
|
| 12:15-13:00 |
Keynote Guest Speaker sponsored by
GlaxoSmithKline
Pemphigus foliaceus and bullous impetigo share a common
pathphysiology.
Prof. John Stanley, Department of Dermatology, University
of Pennsylvania, USA.
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|
| 13:00-14:00 |
Lunch |
SCIENTIFIC SESSION C – Chairman: Sally Ibbotson
| 14:00 |
13
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The effects of TL01 phototherapy
on UVB-induced Langerhans’ cell, CD11b+
and iC3b+ cell trafficking in polymorphic light eruption.
A Blackburn, SM Winhoven, M Brownrigg, LE Rhodes and
NK Gibbs. |
| 14:15 |
14
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Direct real-time electrochemical
measurement and flow cytometry of UVA induced oxidative stress
and its perturbation by mitochondrial electron transport chain
inhibitors. GR Aitken, JR Henderson, S-C Chang, C McNeil
and MA Birch-Machin. |
| 14:30 |
15
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Conjugated linoleic acids exhibit
photoprotective properties, reducing UVR-induced IL-8 and
PGE2 in human skin cells. A Storey, J Rogers, MJ Jackson
and LE Rhodes. |
| 14:45 |
16
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UVA-induced changes in DNA 6-TG
and the development of organ transplant associated cutaneous
malignancies. CM Perrett, P O’Donovan, CA Harwood,
JM McGregor and P Karran. |
| |
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|
| 15:00-15:45 |
British Photodermatology
Group Guest Lecture
Steps in the pathway of ultraviolet a/oxidant-inducible gene
expression in human skin cells – the heme oxygenase example.
Prof. Rex Tyrell, Department of Pharmacy & Pharmacology,
University of Bath, UK. |
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|
| 15:45-17:15 |
Coffee/Tea and Posters |
| |
|
| 17:15-18:30 |
Annual General Meeting |
| |
|
| 19:30-23:30 |
Reception/Dinner sponsored
by 3M Health Care |
Wednesday 13 April 2005
SCIENTIFIC SESSION D – Chairman: Graham Ogg
| 08:45 |
17
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Contribution of cutaneous
interleukin-10 to the polarisation of immune responses to
chemical contact and respiratory allergens. M Cumberbatch,
RJ Dearman and I Kimber. |
| 09:00 |
18
|
TRANCE and its receptors
TRANCE-R and OPG are expressed in human epidermis and regulate
Langerhans’ cell longevity. J-B O Barbaroux, JB
Mee, CG Mueller and RW Groves. |
| 09:15 |
19
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Investigation of Der
P 1-peptide specific T cell responses in individuals with
severe atopic dermatitis. MR Ardern-Jones, EA Bateman,
AS Bailey and GS Ogg. |
| 09:30 |
20
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A novel antimicrobial
photodynamic approach to treat chronic ulcers. SM Morley,
CC O’Grady, SB Brown and LE Rhodes. |
| 09:45 |
21
|
Development of preimplantation
genetic diagnosis for Hallopeau-Siemens recessive dystrophic
epidermolysis bullosa. H Fassihi, C Black, S Pickering,
PJ Renwick, JE Mellerio, PR Braude and JA McGrath. |
| 10:00 |
22
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Disruption of stratum
corneum by microfabricated microneedles for gene delivery
from hydrogels. M Pearton, D Barrow, A Anstey, C Gately,
A Morrissey, N Wilke,
C Allender, K Brain and JC Birchall. |
| |
|
|
| 10:15-11:15 |
|
Coffee/Tea and Posters |
SCIENTIFIC SESSION E – Chairman: Mark Birch-Machin
| 11:15 |
23
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The human forkhead
transcription factor foxm1b enhances DNA repair and
suppresses UVB-induced apoptosis. MT Teh, AG Quinn
and MP Philpott. |
| 11:30 |
24
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Mechanisms of migration
and invasion of squamous cell carcinoma in an in vitro
model of squamous cell carcinogenesis. J Vyas, W Ahmed,
M Jayazeri, JF Marshall, CM Proby, A Storey and EA O’Toole.
|
| 11:45 |
25
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Increased Axl expression in invasive squamous cell carcinoma.
N Patel, J Vyas, L Ghali, J Green, R Cerio, A Storey
and EA O’Toole.
|
| 12:00 |
26
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Gli1 co-operates with
EGFR signalling to induce a neuronal phenotpye in keratinocytes.
GW Neill, M Kasper, T Williams, M Ikram, L Ghali, J
Green, AG Quinn,
A Frischauf, F Aberger, EA O’Toole and MP Philpott. |
| |
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|
| 12:15-13:00 |
Local Guest Speaker
Mutations in the BRAF gene and the implications for melanoma
treatment.
Prof. Mike Stratton, Wellcome Trust Sanger Institute, Cambridge,
UK |
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|
| 13:00-13:05 |
Close of meeting and
prizes |
| 13:05-13:10 |
Collect feedback forms |
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| 13:10-14:00 |
Lunch and depart |
The final poster list (including late-breakers) is available as
a PDF download here:
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